Okayama University Significantly Enhances Anti-Tumor Effects of Hyperthermia with Successful Development of a Novel Sensitizer

A research group at Okayama University has successfully developed a new compound that significantly enhances the therapeutic effects of hyperthermia, a type of cancer treatment. This compound inhibits the formation of 'SAFB granules' within the cell nucleus, which are induced by heat stress. In animal experiments, combining this compound with hyperthermia was confirmed to markedly increase anti-tumor effects. This achievement is expected to lead to the development of new, effective cancer drugs (hyperthermia sensitizers) with fewer side effects. The research findings have been published in a U.S. academic journal.