High-Resolution Visualization of Supramolecular Structures of ATP Synthase and Respiratory Supercomplexes in the Mitochondrial Membrane
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By using cryo-electron microscopy on sub-mitochondrial particles, researchers successfully analyzed mitochondrial inner membrane proteins in their native state. The study identified ATP synthase tetramers and novel configurations of respiratory supercomplexes, paving the way for advanced disease-related mitochondrial research.