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Clinical Study Using Stem Cells from Human Exfoliated Deciduous Teeth for Hypoganglionosis Selected by AMED

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S-Quatre, a group company, has been selected by the Japan Agency for Medical Research and Development (AMED) to conduct a clinical study on using stem cells from human exfoliated deciduous teeth (SHED) to treat hypoganglionosis. This research, conducted in collaboration with Kyushu University, aims to develop a new therapeutic approach for this intractable disease, for which no effective treatment currently exists.

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Frequently Asked Questions

Q: What is the name of the research project selected by AMED involving stem cells from exfoliated deciduous teeth?
A: The research project is titled 'Development of a Novel Treatment for Hypoganglionosis Using Human Exfoliated Deciduous Tooth-Derived Stem Cells' and was selected by AMED for FY2026.
Q: Which company is collaborating with Kyushu University on the clinical study using SHED for hypoganglionosis?
A: S-Quatre Co., Ltd. is collaborating with Kyushu University on the clinical study for hypoganglionosis using SHED as a research collaborator.
Q: Who is the principal investigator of the hypoganglionosis study at Kyushu University Hospital?
A: Lecturer Koichiro Yoshimaru of the Department of Pediatric Surgery at Kyushu University Hospital is the principal investigator of the study.
Q: What role does S-Quatre play in the AMED-funded clinical research project on hypoganglionosis?
A: S-Quatre is responsible for manufacturing and quality control of SHED and contributes expertise in cell manufacturing and clinical development for the project.
Q: Why are SHED considered promising for treating hypoganglionosis in the clinical study?
A: SHED secrete abundant growth factors and cytokines that are expected to promote nerve growth, making them a promising therapeutic approach for hypoganglionosis.