Human Lactoferrin/Human Serum Albumin Fusion Protein Potently Inhibits Cancer Cell Migration Related to Metastasis by Disrupting Golgi pH Homeostasis
NQ Score
50/100
AI Summary (NQ-processed)
A research group at Tokyo University of Technology has discovered that a fusion protein of human lactoferrin and human serum albumin (hLF-HSA) inhibits cancer cell migration by disrupting Golgi apparatus pH homeostasis and activating caveolin-dependent endocytosis. This dual mechanism reduces the expression of MMP1, a key enzyme in cancer metastasis, offering a promising new strategy for drug development.
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