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Triple-Negative Breast Cancer Progresses Rapidly and is Aggressive; Doctors Urge NHI to Cover New Drug as First-Line Treatment

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The Taiwan Breast Cancer Society and physicians are urging the National Health Insurance Administration (NHIA) to advance coverage of antibody-drug conjugates (ADCs) for triple-negative breast cancer from current second-line to first-line treatment. Triple-negative breast cancer progresses rapidly with a poor prognosis, and the 5-year survival rate is only 10%. NHIA Director-General Chen Liang-yu responded that the agency will follow procedures to expand coverage as soon as possible and mentioned that a budget has been allocated for a new cancer drug fund.

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Frequently Asked Questions

Q: What is triple-negative breast cancer?
A: It is a type of breast cancer that tests negative for estrogen receptors, progesterone receptors, and HER2 protein. It is known for its aggressive nature and poor prognosis.
Q: How does an antibody-drug conjugate (ADC) work?
A: An ADC combines a targeted therapy with a chemotherapy drug. It binds specifically to cancer cells and releases the chemotherapy drug inside them, minimizing damage to normal cells.
Q: When can ADCs be used under Taiwan's NHI?
A: Currently, ADCs are covered as a second-line treatment (after chemotherapy has failed). However, doctors are advocating for first-line coverage.