SARABiO Onsen Microorganism Research Institute Co., Ltd. (Headquarters: Beppu City, Oita Prefecture, Representative Director: Takuya Hamada) has discovered a new approach to the relationship between "immune abnormalities," the root cause of allergies and autonomic nervous system imbalances that trouble modern people, and "intestinal environment," in addition to its achievements in extending healthy life expectancy in humans, using the "Onsen-so RG92" (hereinafter referred to as Onsen-so RG92), a hot spring alga isolated from Beppu hot springs and patented. We have started a joint research project with Kanazawa University (Graduate School of Medical Sciences, Division of Medical Sciences) to elucidate new functions at the molecular level through the intestinal environment. ■ Background of Development: "Immune Abnormalities" Facing Modern People and the "Treg" Command Center that Suppresses Runaway Immunity In recent years, there has been a rapid increase in people complaining of allergic diseases (such as hay fever and atopic dermatitis), autonomic nervous system imbalances, and chronic poor health, particularly in developed countries. It is becoming increasingly clear that "immune runaway (breakdown of homeostasis)," where the immune system, which should protect the body, overreacts, is deeply involved in the background of these symptoms. The immune cell known as "regulatory T cells (Treg)" is currently attracting the most attention as the "command center (brake)" that suppresses this immune runaway and balances the overall system. The normal differentiation and activation of Treg in the gut are considered important factors in suppressing allergies and maintaining overall immune balance. Onsen-so RG92 Takes a New Approach to "Immune Abnormalities" ■ Past Achievements: Anti-inflammatory and Metabolic Improvement Effects Confirmed in Clinical Trials on Humans "Onsen-so RG92," a new species of hot spring microalga with high anti-inflammatory effects. In the process of