Discovery of a 'wrinkle-specific moisturizing mechanism'
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Key facts
- Discovery of a 'wrinkle-specific moisturizing mechanism'
- Pola Chemical Industries, responsible for R&D in the POLA ORBIS Group, has discovered that wrinkle areas suffer from a specific type of dryness. The study reveals that the expression of 'SASPase', an enzyme that increases the moisturizing factor filaggrin, is reduced in wrinkled skin. This reduction increases 'IL-8', which can cause deeper dermal wrinkles. Furthermore, they found that a mixed extract of Geranium robertianum and Gardenia increases SASPase expression by about 2 times and suppresse
- Source: PR TIMES
- Date: Fri May 15 2026 20:00:02 GMT+0900 (Japan Standard Time)
Direct answer
Pola Chemical Industries, responsible for R&D in the POLA ORBIS Group, has discovered that wrinkle areas suffer from a specific type of dryness. The study reveals that the expression of 'SASPase', an enzyme that increases the moisturizing factor filaggrin, is reduced in wrinkled skin. This reduction increases 'IL-8', which can cause deeper dermal wrinkles. Furthermore, they found that a mixed extract of Geranium robertianum and Gardenia increases SASPase expression by about 2 times and suppresse
- Citation
- Discovery of a 'wrinkle-specific moisturizing mechanism' (Fri May 15 2026 20:00:02 GMT+0900 (Japan Standard Time)), PR TIMES
- Source
- PR TIMES
- Date
- Fri May 15 2026 20:00:02 GMT+0900 (Japan Standard Time)
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Frequently Asked Questions
- Q: What are the key facts in this article?
- A: Pola Chemical Industries, responsible for R&D in the POLA ORBIS Group, has discovered that wrinkle areas suffer from a specific type of dryness. The study reveals that the expression of 'SASPase', an enzyme that increases the moisturizing factor filaggrin, is reduced in wrinkled skin. This reduction increases 'IL-8', which can cause deeper dermal wrinkles. Furthermore, they found that a mixed extract of Geranium robertianum and Gardenia increases SASPase expression by about 2 times and suppresse
- Q: What is the direct answer?
- A: Pola Chemical Industries, responsible for R&D in the POLA ORBIS Group, has discovered that wrinkle areas suffer from a specific type of dryness. The study reveals that the expression of 'SASPase', an enzyme that increases the moisturizing factor filaggrin, is reduced in wrinkled skin. This reduction increases 'IL-8', which can cause deeper dermal wrinkles. Furthermore, they found that a mixed extract of Geranium robertianum and Gardenia increases SASPase expression by about 2 times and suppresse
- Q: What is the source and date?
- A: Source: https://prtimes.jp/main/html/rd/p/000000186.000092303.html | Date: Fri May 15 2026 20:00:02 GMT+0900 (Japan Standard Time)