Nicorio Co., Ltd. (Head Office: Setagaya-ku, Tokyo; President and CEO: Motohiro Nakagami) announces that research results examining the effects on cognitive function from the intake of capsules containing butyric acid bacteria (Clostridium butyricum), 3-(4-hydroxy-3-methoxyphenyl)propionic acid (hereinafter referred to as HMPA) derived from fermented rice bran, and salmon milt-derived DNA have been published in the medical journal "Shinryo to Shinyaku" (June 2026 issue). This study was a randomized, double-blind, placebo-controlled trial involving 80 middle-aged and older adults aged 55-79 who reported subjective concerns about memory. Participants took one capsule of the test food or a placebo daily for 12 weeks. As a result, in the overall analysis, the number of correct answers in the Symbol Digit Coding (SDC) test, which is related to attention and cognitive processing speed, showed a significant improvement in the test food group compared to the placebo group, as evaluated by Cognitrax (Note 1) for cognitive function. Furthermore, in a subgroup analysis of individuals aged 65 and over with an MMSE-J score (Note 2) of 24-27, significant improvements were confirmed in scores related to verbal memory in the test food group. Additionally, as exploratory evaluations, favorable changes were observed in metabolic indicators such as fasting blood glucose, HbA1c (Note 3), γ-GT (Note 4), and uric acid. On the other hand, no consistent inter-group differences were observed in bowel movement-related indicators. These results suggest that foods combining butyric acid bacteria, HMPA, and salmon milt-derived DNA may support some indicators of cognitive function, and that changes in metabolic status, not just intestinal indicators, may be involved in the background. *1: Cognitrax A computer-based test that evaluates cognitive function. It measures multiple cognitive domains such as memory, attention, and information processing speed. *2: MMSE-J Score A Japanese version of the